Latrophilin fragments behave as independent proteins that associate and signal on binding of LTX(N4C)

Heptahelical, or G-protein-coupled, receptors control many cellular functions and normally consist of one polypeptide chain. In contrast, heptahelical receptors that belong to the long N-terminus, group B (LNB) family are cleaved constitutively into two fragments. The N-terminal fragments (NTFs) res...

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Main Authors: Volynski, Kirill E, Silva, John-Paul, Lelianova, Vera G, Atiqur Rahman, M, Hopkins, Colin, Ushkaryov, Yuri A
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2004
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC526461/
https://ncbi.nlm.nih.gov/pubmed/15483624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600443
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