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Iodine-131 treatment of thyroid cancer cells leads to suppression of cell proliferation followed by induction of cell apoptosis and cell cycle arrest by regulation of B-cell translocation gene 2-mediated JNK/NF-κB pathways

Iodine-131 ((131)I) is widely used for the treatment of thyroid-related diseases. This study aimed to investigate the expression of p53 and BTG2 genes following (131)I therapy in thyroid cancer cell line SW579 and the possible underlying mechanism. SW579 human thyroid squamous carcinoma cells were c...

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Detalhes bibliográficos
Publicado no:Braz J Med Biol Res
Main Authors: Zhao, L.M., Pang, A.X.
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264532/
https://ncbi.nlm.nih.gov/pubmed/28099584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20165933
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