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Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H(2)O(2)‐induced PC12 cells death by inhibiting mitochondria‐mediated autophagy

Oxidative stress is a major cause of cellular injury in a variety of human diseases including neurodegenerative disorders. Thus, removal of excessive reactive oxygen species (ROS) or suppression of ROS generation may be effective in preventing oxidative stress‐induced cell death. This study was desi...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Gao, Jianmei, Deng, Yuanyuan, Yin, Caixia, Liu, Yuangui, Zhang, Wei, Shi, Jingshan, Gong, Qihai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264130/
https://ncbi.nlm.nih.gov/pubmed/27642051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12971
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