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α-Defensin HD5 Inhibits Human Papillomavirus 16 Infection via Capsid Stabilization and Redirection to the Lysosome

α-Defensins are an important class of abundant innate immune effectors that are potently antiviral against a number of nonenveloped viral pathogens; however, a common mechanism to explain their ability to block infection by these unrelated viruses is lacking. We previously found that human defensin...

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Pubblicato in:mBio
Autori principali: Wiens, Mayim E., Smith, Jason G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263252/
https://ncbi.nlm.nih.gov/pubmed/28119475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02304-16
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