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Alpha-Defensin HD5 Inhibits Furin Cleavage of Human Papillomavirus 16 L2 To Block Infection

Human papillomavirus (HPV) is a significant oncogenic virus, but the innate immune response to HPV is poorly understood. Human α-defensin 5 (HD5) is an innate immune effector peptide secreted by epithelial cells in the genitourinary tract. HD5 is broadly antimicrobial, exhibiting potent antiviral ac...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wiens, Mayim E., Smith, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325740/
https://ncbi.nlm.nih.gov/pubmed/25540379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02901-14
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