Pseudomonas aeruginosa Pore-Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis

Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, ExlB, showing that ExlA and ExlB define a new active two-part...

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Publicat a:mBio
Autors principals: Basso, Pauline, Ragno, Michel, Elsen, Sylvie, Reboud, Emeline, Golovkine, Guillaume, Bouillot, Stephanie, Huber, Philippe, Lory, Stephen, Faudry, Eric, Attrée, Ina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263249/
https://ncbi.nlm.nih.gov/pubmed/28119472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02250-16
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