Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by self-renewal. However, the precise temporal and spatial dynamics of the microglial population are unknown. We show in mice and humans that the...

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Publicat a:Cell Rep
Autors principals: Askew, Katharine, Li, Kaizhen, Olmos-Alonso, Adrian, Garcia-Moreno, Fernando, Liang, Yajie, Richardson, Philippa, Tipton, Tom, Chapman, Mark A., Riecken, Kristoffer, Beccari, Sol, Sierra, Amanda, Molnár, Zoltán, Cragg, Mark S., Garaschuk, Olga, Perry, V. Hugh, Gomez-Nicola, Diego
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263237/
https://ncbi.nlm.nih.gov/pubmed/28076784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.041
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