IL-10 Receptor Signaling is essential for T(R)1 cell function in vivo

Interleukin-10 (IL-10) is essential to maintain intestinal homeostasis. CD4(+) T regulatory type 1 (T(R)1) cells produce large amounts of this cytokine and being therefore currently examined in clinical trials as T-cell therapy in patients with inflammatory bowel disease (IBD). However, factors and...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Brockmann, Leonie, Gagliani, Nicola, Steglich, Babett, Giannou, Anastasios D., Kempski, Jan, Pelczar, Penelope, Geffken, Maria, Mfarrej, Bechara, Huber, Francis, Herkel, Johannes, Wan, Yisong Y., Esplugues, Enric, Battaglia, Manuela, Krebs, Christian F., Flavell, Richard A., Huber, Samuel
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263184/
https://ncbi.nlm.nih.gov/pubmed/28003377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601045
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