New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease

Background and Aims: Drug-induced steatosis is a major reason for drug failure in clinical trials and post-marketing withdrawal; and therefore, predictive biomarkers are essential. These could be particularly relevant in non-alcoholic fatty liver disease (NAFLD), where most patients show features of...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: López-Riera, Mireia, Conde, Isabel, Tolosa, Laia, Zaragoza, Ángela, Castell, José V., Gómez-Lechón, María J., Jover, Ramiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263149/
https://ncbi.nlm.nih.gov/pubmed/28179883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00003
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