Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers

BACKGROUND: Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs. METHODS: XenoMouse(®)-G2 animals wer...

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Hlavní autoři: Garambois, Véronique, Glaussel, Fabienne, Foulquier, Elodie, Ychou, Marc, Pugnière, Martine, Luo, Robin X, Bezabeh, Binyam, Pèlegrin, André
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC526287/
https://ncbi.nlm.nih.gov/pubmed/15488142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-75
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