Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers

BACKGROUND: Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs. METHODS: XenoMouse(®)-G2 animals wer...

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Detalhes bibliográficos
Main Authors: Garambois, Véronique, Glaussel, Fabienne, Foulquier, Elodie, Ychou, Marc, Pugnière, Martine, Luo, Robin X, Bezabeh, Binyam, Pèlegrin, André
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC526287/
https://ncbi.nlm.nih.gov/pubmed/15488142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-75
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