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Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis

Decoy receptor 3 (DcR3) has been recently described as an antiapoptosis and prometastasis factor since it can competitively bind to FasL, TL1A, and LIGHT, and it is highly expressed in many malignant tumors. Downregulation of DcR3 can promote tumor cell apoptosis and inhibit metastasis. A previous s...

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Publicat a:Onco Targets Ther
Autors principals: Liang, Chaojie, Xu, Yingchen, Li, Guangming, Zhao, Tuanjie, Xia, Feng, Li, Guanqun, Zhang, Dongxin, Wu, Jixiang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261847/
https://ncbi.nlm.nih.gov/pubmed/28176915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S127202
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