Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis

BACKGROUND: Dysregulation of many apoptotic related genes and androgens are critical in the development, progression, and treatment of prostate cancer. The differential sensitivity of tumour cells to TRAIL-induced apoptosis can be mediated by the modulation of surface TRAIL receptor expression relat...

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Main Authors: Vindrieux, David, Réveiller, Marie, Chantepie, Jacqueline, Yakoub, Sadok, Deschildre, Catherine, Ruffion, Alain, Devonec, Marian, Benahmed, Mohamed, Grataroli, Renée
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Primary Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286382/
https://ncbi.nlm.nih.gov/pubmed/22136382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-42
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