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Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

The RAD6 gene of Saccharomyces cerevisiae encodes a ubiquitin-conjugating enzyme (E2) that is required for DNA repair, damage-induced mutagenesis, and sporulation. We have cloned the two human RAD6 homologs, designated HHR6A and HHR6B. The two 152-amino acid human proteins share 95% sequence identit...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Koken, M H, Reynolds, P, Jaspers-Dekker, I, Prakash, L, Prakash, S, Bootsma, D, Hoeijmakers, J H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.8865
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