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RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.

Xeroderma pigmentosum (XP) patients are extremely sensitive to ultraviolet (UV) light and suffer from a high incidence of skin cancers, due to a defect in nucleotide excision repair. The disease is genetically heterogeneous, and seven complementation groups, A-G, have been identified. Homologs of hu...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Park, E, Guzder, S N, Koken, M H, Jaspers-Dekker, I, Weeda, G, Hoeijmakers, J H, Prakash, S, Prakash, L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1333609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11416
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