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PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control
Mitochondrial dysfunction has been linked to the pathogenesis of a large number of inherited diseases in humans, including Parkinson's disease, the second most common neurodegenerative disorder. The Parkinson's disease genes pink1 and parkin, which encode a mitochondrially targeted protein...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5261015/ https://ncbi.nlm.nih.gov/pubmed/27906179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.396 |
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