Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection

The amyloid beta (Aβ) pathway is strongly implicated in neurodegenerative conditions such as Alzheimer's disease and more recently, glaucoma. Here, we identify the α2 adrenergic receptor agonists (α2ARA) used to lower intraocular pressure can prevent retinal ganglion cell (RGC) death via the no...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Nizari, Shereen, Guo, Li, Davis, Benjamin M, Normando, Eduardo M, Galvao, Joana, Turner, Lisa A, Bizrah, Mukhtar, Dehabadi, Mohammad, Tian, Kailin, Francesca Cordeiro, M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260990/
https://ncbi.nlm.nih.gov/pubmed/27929541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.397
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