Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection

The amyloid beta (Aβ) pathway is strongly implicated in neurodegenerative conditions such as Alzheimer's disease and more recently, glaucoma. Here, we identify the α2 adrenergic receptor agonists (α2ARA) used to lower intraocular pressure can prevent retinal ganglion cell (RGC) death via the no...

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Vydáno v:Cell Death Dis
Hlavní autoři: Nizari, Shereen, Guo, Li, Davis, Benjamin M, Normando, Eduardo M, Galvao, Joana, Turner, Lisa A, Bizrah, Mukhtar, Dehabadi, Mohammad, Tian, Kailin, Francesca Cordeiro, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260990/
https://ncbi.nlm.nih.gov/pubmed/27929541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.397
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