The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling

Among all tissues and organs, the mammary gland is unique because most of its development occurs in adulthood. Notch signaling has a major role in mammary gland development and has been implicated in breast cancer. The vacuolar-ATPase (V-ATPase) is a proton pump responsible for the regulation and co...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Pamarthy, Sahithi, Mao, Liquin, Katara, Gajendra K, Fleetwood, Sara, Kulshreshta, Arpita, Gilman-Sachs, Alice, Beaman, Kenneth D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260869/
https://ncbi.nlm.nih.gov/pubmed/27809299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.347
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