Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

The Parkinson's disease (PD)-related protein F-box only protein 7 (Fbxo7) is the substrate-recognition component of the Skp1-Cullin-F-box protein E3 ubiquitin ligase complex. We have recently shown that PD-associated mutations in Fbxo7 disrupt mitochondrial autophagy (mitophagy), suggesting a r...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Delgado-Camprubi, Marta, Esteras, Noemi, Soutar, Marc PM, Plun-Favreau, Helene, Abramov, Andrey Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260490/
https://ncbi.nlm.nih.gov/pubmed/27689878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.104
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars