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An ensemble micro neural network approach for elucidating interactions between zinc finger proteins and their target DNA

BACKGROUND: The ability to engineer zinc finger proteins binding to a DNA sequence of choice is essential for targeted genome editing to be possible. Experimental techniques and molecular docking have been successful in predicting protein-DNA interactions, however, they are highly time and resource...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: Dutta, Shayoni, Madan, Spandan, Parikh, Harsh, Sundar, Durai
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260015/
https://ncbi.nlm.nih.gov/pubmed/28155662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3323-9
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