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Exploiting the recognition code for elucidating the mechanism of zinc finger protein-DNA interactions
BACKGROUND: Engineering zinc finger protein motifs for specific binding to double-stranded DNA is critical for targeted genome editing. Most existing tools for predicting DNA-binding specificity in zinc fingers are trained on data obtained from naturally occurring proteins, thereby skewing the predi...
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| Опубликовано в: : | BMC Genomics |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260074/ https://ncbi.nlm.nih.gov/pubmed/28155654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3324-8 |
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