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Permeability across a novel microfluidic blood-tumor barrier model

BACKGROUND: The lack of translatable in vitro blood-tumor barrier (BTB) models creates challenges in the development of drugs to treat tumors of the CNS and our understanding of how the vascular changes at the BBB in the presence of a tumor. METHODS: In this study, we characterize a novel microfluid...

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Publicado en:Fluids Barriers CNS
Main Authors: Terrell-Hall, Tori B., Ammer, Amanda G., Griffith, Jessica I. G., Lockman, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260004/
https://ncbi.nlm.nih.gov/pubmed/28114946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0050-9
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