Evaluating the effect of database inflation in proteogenomic search on sensitive and reliable peptide identification

BACKGROUND: Proteogenomics is a promising approach for various tasks ranging from gene annotation to cancer research. Databases for proteogenomic searches are often constructed by adding peptide sequences inferred from genomic or transcriptomic evidence to reference protein sequences. Such inflation...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Li, Honglan, Joh, Yoon Sung, Kim, Hyunwoo, Paek, Eunok, Lee, Sang-Won, Hwang, Kyu-Baek
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259817/
https://ncbi.nlm.nih.gov/pubmed/28155652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3327-5
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