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Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

[Image: see text] Lipoarabinomannan (LAM) and arabinogalactan (AG) are the two major mycobacterial cell wall (lipo)polysaccharides, which contain a structurally similar arabinan domain that is highly branched and assembled in a stepwise fashion by variety of arabinofuranosyltransferases (ArafT). In...

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Publicat a:ACS Chem Biol
Autors principals: Jankute, Monika, Alderwick, Luke J., Noack, Stephan, Veerapen, Natacha, Nigou, Jérôme, Besra, Gurdyal S.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259755/
https://ncbi.nlm.nih.gov/pubmed/28033704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00898
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