Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury

Ependyma have been proposed as adult neural stem cells that provide the majority of newly proliferated scar-forming astrocytes that protect tissue and function after spinal cord injury (SCI). This proposal was based on small, midline stab SCI. Here, we tested the generality of this proposal by using...

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Pubblicato in:Sci Rep
Autori principali: Ren, Yilong, Ao, Yan, O’Shea, Timothy M., Burda, Joshua E., Bernstein, Alexander M., Brumm, Andrew J., Muthusamy, Nagendran, Ghashghaei, H. Troy, Carmichael, S. Thomas, Cheng, Liming, Sofroniew, Michael V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259707/
https://ncbi.nlm.nih.gov/pubmed/28117356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41122
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