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Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients

CDX1 and CDX2 are possibly predictive biomarkers in colorectal cancer. We combined digitally‐guided (next generation) TMA construction (ngTMA) and the utility of digital image analysis (DIA) to assess accuracy, tumour heterogeneity and the selective impact of different combined intensity‐percentage...

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Библиографические подробности
Опубликовано в: :J Pathol Clin Res
Главные авторы: Nolte, Sarah, Zlobec, Inti, Lugli, Alessandro, Hohenberger, Werner, Croner, Roland, Merkel, Susanne, Hartmann, Arndt, Geppert, Carol I, Rau, Tilman T
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259563/
https://ncbi.nlm.nih.gov/pubmed/28138402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.62
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