Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients

CDX1 and CDX2 are possibly predictive biomarkers in colorectal cancer. We combined digitally‐guided (next generation) TMA construction (ngTMA) and the utility of digital image analysis (DIA) to assess accuracy, tumour heterogeneity and the selective impact of different combined intensity‐percentage...

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Veröffentlicht in:J Pathol Clin Res
Hauptverfasser: Nolte, Sarah, Zlobec, Inti, Lugli, Alessandro, Hohenberger, Werner, Croner, Roland, Merkel, Susanne, Hartmann, Arndt, Geppert, Carol I, Rau, Tilman T
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259563/
https://ncbi.nlm.nih.gov/pubmed/28138402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.62
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