High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancer

Cancer‐associated fibroblasts (CAFs) regulate tumour growth, metastasis and response to treatment. Recent studies indicate the existence of functionally distinct CAF subsets. Suggested mechanisms whereby CAFs can impact on treatment response include paracrine signalling affecting cancer cell drug se...

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Detalhes bibliográficos
Publicado no:J Pathol Clin Res
Main Authors: Paulsson, Janna, Rydén, Lisa, Strell, Carina, Frings, Oliver, Tobin, Nicholas P, Fornander, Tommy, Bergh, Jonas, Landberg, Göran, Stål, Olle, Östman, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259559/
https://ncbi.nlm.nih.gov/pubmed/28138400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.56
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