High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancer

Cancer‐associated fibroblasts (CAFs) regulate tumour growth, metastasis and response to treatment. Recent studies indicate the existence of functionally distinct CAF subsets. Suggested mechanisms whereby CAFs can impact on treatment response include paracrine signalling affecting cancer cell drug se...

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Dettagli Bibliografici
Pubblicato in:J Pathol Clin Res
Autori principali: Paulsson, Janna, Rydén, Lisa, Strell, Carina, Frings, Oliver, Tobin, Nicholas P, Fornander, Tommy, Bergh, Jonas, Landberg, Göran, Stål, Olle, Östman, Arne
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259559/
https://ncbi.nlm.nih.gov/pubmed/28138400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.56
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