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Low ERK Phosphorylation in Cancer-Associated Fibroblasts Is Associated with Tamoxifen Resistance in Pre-Menopausal Breast Cancer

PURPOSE: The aim of this study was to evaluate ERK phosphorylation as a stromal biomarker for breast cancer prognosis and tamoxifen treatment prediction within a randomized tamoxifen trial. PATIENTS AND METHODS: Tissue microarrays of two breast cancer cohorts including in total 743 invasive breast c...

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Detalhes bibliográficos
Main Authors: Busch, Susann, Rydén, Lisa, Stål, Olle, Jirström, Karin, Landberg, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454403/
https://ncbi.nlm.nih.gov/pubmed/23029174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045669
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