Veliparib in combination with whole-brain radiation therapy for patients with brain metastases from non-small cell lung cancer: results of a randomized, global, placebo-controlled study

Veliparib is a potent, orally bioavailable, poly (adenosine diphosphate-ribose) polymerase (PARP) inhibitor that crosses the blood–brain barrier and has been shown to potentiate the effects of radiation in preclinical and early clinical studies. This phase 2, randomized, global study evaluated the e...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Chabot, Pierre, Hsia, Te-Chun, Ryu, Jeong-Seon, Gorbunova, Vera, Belda-Iniesta, Cristobal, Ball, David, Kio, Ebenezer, Mehta, Minesh, Papp, Katherine, Qin, Qin, Qian, Jane, Holen, Kyle D., Giranda, Vince, Suh, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258788/
https://ncbi.nlm.nih.gov/pubmed/27655223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-016-2275-x
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