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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep

Orf virus (ORFV) is the type species of the Parapoxvirus genus of the family Poxviridae and infects sheep and goats, often around the mouth, resulting in acute pustular skin lesions. ORFV encodes several secreted immunomodulators including a broad-spectrum chemokine binding protein (CBP). Chemokines...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Front Microbiol
Päätekijät: Fleming, Stephen B., McCaughan, Catherine, Lateef, Zabeen, Dunn, Amy, Wise, Lyn M., Real, Nicola C., Mercer, Andrew A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258736/
https://ncbi.nlm.nih.gov/pubmed/28174562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00046
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