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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep

Orf virus (ORFV) is the type species of the Parapoxvirus genus of the family Poxviridae and infects sheep and goats, often around the mouth, resulting in acute pustular skin lesions. ORFV encodes several secreted immunomodulators including a broad-spectrum chemokine binding protein (CBP). Chemokines...

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Detaylı Bibliyografya
Yayımlandı:Front Microbiol
Asıl Yazarlar: Fleming, Stephen B., McCaughan, Catherine, Lateef, Zabeen, Dunn, Amy, Wise, Lyn M., Real, Nicola C., Mercer, Andrew A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258736/
https://ncbi.nlm.nih.gov/pubmed/28174562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00046
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