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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep

Orf virus (ORFV) is the type species of the Parapoxvirus genus of the family Poxviridae and infects sheep and goats, often around the mouth, resulting in acute pustular skin lesions. ORFV encodes several secreted immunomodulators including a broad-spectrum chemokine binding protein (CBP). Chemokines...

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書目詳細資料
發表在:Front Microbiol
Main Authors: Fleming, Stephen B., McCaughan, Catherine, Lateef, Zabeen, Dunn, Amy, Wise, Lyn M., Real, Nicola C., Mercer, Andrew A.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258736/
https://ncbi.nlm.nih.gov/pubmed/28174562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00046
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