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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep

Orf virus (ORFV) is the type species of the Parapoxvirus genus of the family Poxviridae and infects sheep and goats, often around the mouth, resulting in acute pustular skin lesions. ORFV encodes several secreted immunomodulators including a broad-spectrum chemokine binding protein (CBP). Chemokines...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Fleming, Stephen B., McCaughan, Catherine, Lateef, Zabeen, Dunn, Amy, Wise, Lyn M., Real, Nicola C., Mercer, Andrew A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258736/
https://ncbi.nlm.nih.gov/pubmed/28174562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00046
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