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Requirement of protein synthesis for the degradation of host mRNA in Friend erythroleukemia cells infected wtih herpes simplex virus type 1.

We describe experiments which demonstrate that shortly after infection of Friend erythroleukemia cells with herpes simplex virus (HSV), polyribosomes dissociate and cellular mRNA degrades. Analysis of infected cell extracts on sucrose density gradients demonstrates that the majority of the polyribos...

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Bibliographic Details
Published in:J Virol
Main Authors: Nishioka, Y, Silverstein, S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/212585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.27.3.619-627.1978
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