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Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.

Synthesis of erythropoietin, the primary humoral regulator of erythropoiesis, in liver and kidney is inducible by anemia or hypoxia. Analysis of human erythropoietin gene expression in transgenic mice revealed that sequences located 6-14 kilobases 5' to the gene direct expression to the kidney, wher...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Semenza, G L, Koury, S T, Nejfelt, M K, Gearhart, J D, Antonarakis, S E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924331/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8725
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