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Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.

Synthesis of erythropoietin, the primary humoral regulator of erythropoiesis, in liver and kidney is inducible by anemia or hypoxia. Analysis of human erythropoietin gene expression in transgenic mice revealed that sequences located 6-14 kilobases 5' to the gene direct expression to the kidney,...

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Detalhes bibliográficos
Main Authors: Semenza, G L, Koury, S T, Nejfelt, M K, Gearhart, J D, Antonarakis, S E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52582/
https://ncbi.nlm.nih.gov/pubmed/1924331
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