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Expansion and productive HIV-1 infection of Foxp3 positive CD4 T cells at pleural sites of HIV/TB co-infection

BACKGROUND: CD4 T-cells expressing Foxp3 are expanded systemically during active tuberculosis (TB) regardless of HIV-1 co-infection. Foxp3(+) CD4 T cells are targets of HIV-1 infection. However, expansion of HIV-1 infected Foxp3(+) CD4 T cells at sites of HIV/TB co-infection, and whether they contri...

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Pubblicato in:J Clin Exp Immunol
Autori principali: Hirsch, Christina S, Baseke, Joy, Kafuluma, John Lusiba, Nserko, Mary, Mayanja-Kizza, Harriet, Toossi, Zahra
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258182/
https://ncbi.nlm.nih.gov/pubmed/28124031
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