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Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort

Prenatal exposure to lead (Pb) is known to decrease fetal growth; but its effects on postnatal growth and mechanistic insights linking Pb to growth are not clearly defined. Genomically imprinted genes are powerful regulators of growth and energy utilization, and may be particularly vulnerable to env...

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Detalhes bibliográficos
Publicado no:Environ Epigenet
Main Authors: Nye, Monica D., King, Katherine E., Darrah, Thomas H., Maguire, Rachel, Jima, Dereje D., Huang, Zhiqing, Mendez, Michelle A., Fry, Rebecca C., Jirtle, Randy L., Murphy, Susan K., Hoyo, Cathrine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258134/
https://ncbi.nlm.nih.gov/pubmed/28123784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvv009
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