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Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over again

The Randle cycle, which has been invoked to explain the reciprocal relationship between fatty acid oxidation and glucose oxidation, has long been implicated as a potential mechanism for hyperglycemia and type 2 diabetes mellitus (T2DM). Now genetic, functional genomic, and transgenic approaches have...

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Autori principali: Shuldiner, Alan R., McLenithan, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC525752/
https://ncbi.nlm.nih.gov/pubmed/15545992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423586
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