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Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over again

The Randle cycle, which has been invoked to explain the reciprocal relationship between fatty acid oxidation and glucose oxidation, has long been implicated as a potential mechanism for hyperglycemia and type 2 diabetes mellitus (T2DM). Now genetic, functional genomic, and transgenic approaches have...

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Detalhes bibliográficos
Main Authors: Shuldiner, Alan R., McLenithan, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525752/
https://ncbi.nlm.nih.gov/pubmed/15545992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423586
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