Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

BACKGROUND: Major trauma is a leading cause of morbidity and mortality worldwide with hemorrhage accounting for 40% of deaths. Acute Traumatic Coagulopathy (ATC) exacerbates bleeding but controversy remains over the degree to which inhibition of procoagulant pathways (anticoagulation), fibrinogen lo...

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Gepubliceerd in:Anesthesiology
Hoofdauteurs: Davenport, Ross A, Guerreiro, Maria, Frith, Daniel, Rourke, Claire, Platton, Sean, Cohen, Mitchell, Pearse, Rupert, Thiemermann, Chris, Brohi, Karim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257267/
https://ncbi.nlm.nih.gov/pubmed/27841821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001428
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