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THE DUALITY OF FGL2 - SECRETED IMMUNE CHECKPOINT REGULATOR VERSUS MEMBRANE-ASSOCIATED PROCOAGULANT: THERAPEUTIC POTENTIAL AND IMPLICATIONS
Fibrinogen-like protein 2 (Fgl2), a member of the fibrinogen family, can be expressed as a membrane-associated protein with coagulation activity or in a secreted form possessing unique immune suppressive functions. The biological importance of Fgl2 is evident within viral-induced fibrin depositing i...
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Publicado no: | Int Rev Immunol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5257246/ https://ncbi.nlm.nih.gov/pubmed/25259408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08830185.2014.956360 |
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