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THE DUALITY OF FGL2 - SECRETED IMMUNE CHECKPOINT REGULATOR VERSUS MEMBRANE-ASSOCIATED PROCOAGULANT: THERAPEUTIC POTENTIAL AND IMPLICATIONS

Fibrinogen-like protein 2 (Fgl2), a member of the fibrinogen family, can be expressed as a membrane-associated protein with coagulation activity or in a secreted form possessing unique immune suppressive functions. The biological importance of Fgl2 is evident within viral-induced fibrin depositing i...

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Detalhes bibliográficos
Publicado no:Int Rev Immunol
Main Authors: Hu, Jiemiao, Yan, Jun, Rao, Ganesh, Latha, Khatri, Overwijk, Willem W., Heimberger, Amy B, Li, Shulin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257246/
https://ncbi.nlm.nih.gov/pubmed/25259408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08830185.2014.956360
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