β2–Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression

PURPOSE: The role of β–adrenergic receptor (AR) signaling in neovascular ocular diseases has recently emerged. We have previously reported that intraperitoneal propranolol inhibits choroidal neovascularization (CNV) in vivo and β2-AR blockade reduces vascular endothelial growth factor (VEGF) express...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Lavine, Jeremy A., Farnoodian, Mitra, Wang, Shoujian, Darjatmoko, Soesiawati R., Wright, Lynda S., Gamm, David M., Ip, Michael S., Sorenson, Christine M., Sheibani, Nader
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256681/
https://ncbi.nlm.nih.gov/pubmed/28114591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20204
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