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Regulator of G Protein Signaling 17 as a Negative Modulator of GPCR Signaling in Multiple Human Cancers

Regulators of G protein signaling (RGS) proteins modulate G protein-coupled receptor (GPCR) signaling networks by terminating signals produced by active Gα subunits. RGS17, a member of the RZ subfamily of RGS proteins, is typically only expressed in appreciable amounts in the human central nervous s...

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Bibliographic Details
Published in:AAPS J
Main Authors: Hayes, Michael P., Roman, David L.
Format: Artigo
Language:Inglês
Published: Springer US 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256612/
https://ncbi.nlm.nih.gov/pubmed/26928451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-9894-1
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