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Aggregation Kinetics for IgG1-Based Monoclonal Antibody Therapeutics

Monoclonal antibodies (mAbs) as a class of therapeutic molecules are finding an increasing demand in the biotechnology industry for the treatment of diseases like cancer and multiple sclerosis. A key challenge associated to successful commercialization of mAbs is that from the various physical and c...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Singla, A., Bansal, R., Joshi, Varsha, Rathore, Anurag S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256606/
https://ncbi.nlm.nih.gov/pubmed/26902302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-9887-0
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