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Mutation in the primer binding site of the type 1 human immunodeficiency virus genome affects virus production and infectivity.
In an effort to understand the contribution of the primer-binding site (PBS) region to human immunodeficiency virus (HIV) replication, we have constructed a mutant HIV proviral DNA with an alteration in the 5' end of the PBS. The PBS mutant proviral DNA was characterized by transfection of the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.4114 |
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