Mutation in the primer binding site of the type 1 human immunodeficiency virus genome affects virus production and infectivity.

In an effort to understand the contribution of the primer-binding site (PBS) region to human immunodeficiency virus (HIV) replication, we have constructed a mutant HIV proviral DNA with an alteration in the 5' end of the PBS. The PBS mutant proviral DNA was characterized by transfection of the...

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Detalhes bibliográficos
Main Authors: Nagashunmugam, T, Velpandi, A, Goldsmith, C S, Zaki, S R, Kalyanaraman, V S, Srinivasan, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525643/
https://ncbi.nlm.nih.gov/pubmed/1373895
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