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Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction

Previously, we found that brain‐derived neurotrophic factor (BDNF) signaling through the high‐affinity tropomyosin‐related kinase receptor subtype B (TrkB) enhances neuromuscular transmission in the diaphragm muscle. However, there is an age‐related loss of this effect of BDNF/TrkB signaling that ma...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Autores principales: Greising, Sarah M., Vasdev, Amrit K., Zhan, Wen‐Zhi, Sieck, Gary C., Mantilla, Carlos B.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256161/
https://ncbi.nlm.nih.gov/pubmed/28082429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13103
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