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The V‐ATPase is expressed in the choroid plexus and mediates cAMP‐induced intracellular pH alterations

The cerebrospinal fluid (CSF) pH influences brain interstitial pH and, therefore, brain function. We hypothesized that the choroid plexus epithelium (CPE) expresses the vacuolar H(+)‐ATPase (V‐ATPase) as an acid extrusion mechanism in the luminal membrane to counteract detrimental elevations in CSF...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Christensen, Henriette L., Păunescu, Teodor G., Matchkov, Vladimir, Barbuskaite, Dagne, Brown, Dennis, Damkier, Helle H., Praetorius, Jeppe
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256157/
https://ncbi.nlm.nih.gov/pubmed/28053225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13072
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